Two Cases of Multiple Eccrine Hidrocystomas with Good Response to Botulinum Toxin

Multiple eccrine hidrocystomas of the face are rare benign cystic lesions characterized by numerous asymptomatic, fl esh-colored, mild, and translucent facial papules in middle-aged women. The condition often runs a chronic course, which may be exacerbated by seasonal change or heat exposure. Topical application of 1% atropine is the conventional treatment option, but the results are not always satisfying. Here, we present the clinicopathological features of and treatment modality for two middle-aged female patients with multiple eccrine hidrocystomas. They achieved rapid clearing of the skin lesions (<1 week) on treatment with the fi rst course of botulinum toxin injection. (Dermatol Sinica 27: 186-191, 2009)